Cyclizine hydrochloride summary of product characteristics. If you have any further questions, ask your doctor or. Oral cyclizine is indicated for the prophylaxis and treatment of nausea, vomiting and dizziness associated with motion sickness. This side effect usually resolved within hours following discontinuation of treatment. Cyclizine hydrochloride is a hydrochloride salt consisting of equimolar amounts of cyclizine and hydrogen chloride. As cyclizine hydrochloride tablets and cyclizine lactate solution for intramuscular or intravenous injection brand names. It will be referred to as cyclizine hydrochloride tablets for ease hereafter.
It may also be used for nausea after general anaesthesia or that which developed from opioid use. It is a histamine h1 antagonist given by mouth or parenterally for the control of postoperative and druginduced vomiting and in motion sickness. Hazardous gasesvapors produced are hypochlorous acid, chlorine and hydrochloric acid. Cyclizine may precipitate at concentrations above 10 mgml or in the presence of sodium chloride 0. Cyclizine may also be used for purposes not listed in this medication guide. Structure, properties, spectra, suppliers and links for. Cyclizine hydrochloride tablets may be used by adults and children aged 6 years and over. Cyclizine is only found in individuals that have used or taken this drug. Indications, dose, contraindications, sideeffects, interactions, cautions, warnings and other safety information for dipipanone hydrochloride with cyclizine. Cyclizine hydrochloride manufacturerhigh qualitybest pricein stock. It has a role as a h1receptor antagonist, a central nervous system depressant, a cholinergic antagonist and an antiemetic. These medications may interact and cause very harmful effects. Composition depends upon temperature and decrease in ph.
Find patient medical information for cyclizine oral on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Section b, structural science 368 august 1980 with 110 reads. See what others have said about cyclizine, including the effectiveness, ease of use and side effects. Continuousflow multistep synthesis of cinnarizine, cyclizine. Cyclizine 50mg tablets patient information leaflet pil. Buy cyclizine hydrochloride cas 303253, a piperazine derivative with antiemetic activity, from santa cruz. View as pdf for printing view as latex for geeks switch colors pharms cyclizine 234.
What you need to know before you take cyclizine hydrochloride tablets 3. Nov 09, 2018 cyclizine is used to treat or prevent nausea, vomiting, or dizziness caused by motion sickness. Qualitative and quantitative composition each tablet contains 50 mg cyclizine hydrochloride for the full list of excipients, see section 6. A few studies have reported on cyclizine abuse among teenagers, and cyclizine abuse has been reported among opioid dependants receiving methadone, with the combination having been reported to produce strong psychoactive effects. Toxicology and hazard communication pfizer global environment, health, and safety operations pfizer inc believes that the information contained in this material safety data sheet is accurate, and while it is provided in good faith, it is without warranty of any kind, expressed or implied.
P264 wash contaminated skin thoroughly after handling. Product information for auspar valoid cyclizine lactate link medical products pty ltd pm20100357331 final 15 january 20. Sds of cyclizine hydrochloride, safety data sheets, cas. Description of first aid measures general information get medical adviceattention if you feel unwell. Paralysis was reported with iv formulations and typically affected the limbs within minutes of administration. Cyclizie is a medication used in the treatment and prevention of nausea, dizziness and vomiting due to vertigo or motion sickness. Cyclizine hydrochloride 50 mg tablets cyclizine hydrochloride read all of this leaflet carefully before you start taking this medicine because it contains important information for you. Cinnarizine, cyclizine, buclizine, and meclizine belong to a family of antihistamines that resemble each other in terms of a 1diphenylmethylpiperazine moiety.
The resultant ethylene amine hydrochloride solution is neutralised with caustic. What cyclizine hydrochloride tablets are and what they are used for 2. Page 37 safety data sheet according to 19072006ec, article 31 printing date 05. This chemicals molecular formula is c 18 h 23 cln 2 and molecular weight is 302. Identification of the substancepreparation and of the. Pharmaceutical form tablet white, circular, biconvex tablet with a break line on one side and plain on the other the tablet can be divided into equal doses 4. Buy cyclizine hydrochloride cas 303253, a piperazine derivative with. Cyclizine hydrochloride cas 303253 scbt santa cruz.
Ensure that medical personnel are aware of the materials involved and take precautions to protect themselves. We present the development of a fourstep continuous process to generate the final antihistamines from bulk alcohols as the starting compounds. H361 suspected of damaging fertility or the unborn child. If tablets or capsules are crushed andor broken, avoid breathing dust and avoid contact with eyes, skin, and clothing. Bonine for kids, cyclivert, marezine cyclizine uses, side. The name of your medicine is cyclizine hydrochloride 50 mg tablets. Ask your doctor before taking cyclizine with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures. Cyclizine hydrochloride tablets contain the active substance cyclizine hydrochloride, which belongs to a group of medicines called antihistamines which can be used to help stop you feeling sick nausea or being sick vomiting. Material safety data sheet sodium hypochlorite unil. Explosion limits in air are given in the safety data sheet. Because of its anticholinergic activity cyclizine may enhance the sideeffects of other anticholinergic drugs. All reports are erowid and you agree not to download or analyze the report data without contacting erowid center and receiving permission first. Cyclizine tablets enhances the soporific effect of pethidine.
Synonyms cyclizine chloride cyclizine hcl unii w0o1nhp4we cas number 303253 weight average. Each tablet contains 50 mg cyclizine hydrochloride. This product information was approved at the time this auspar was published. Precautionary statements p201 obtain special instructions before use. Shake a quantity of finely powdered tablets, equivalent to about 500 mg of cyclizine hydrochloride, with 25 ml of water for 5 minutes, and filter the mixture. Cyclizine is used to treat or prevent nausea, vomiting, or dizziness caused by motion sickness.
Depressed levels of consciousness, loss of consciousness. Dipipanone hydrochloride with cyclizine drug bnf content. Identification of the substancemixture and of the companyundertaking product name. Inhalation remove person to fresh air and keep comfortable for breathing. Cyclizine hydrochloride article pdf available in acta crystallographica. Page 27 safety data sheet according to 19072006ec, article 31 printing date 05. The cyclizine hydrochloride, with the cas registry number 303253, is also known as 1diphenylmethyl4methylpiperazine monohydrochloride. Cyclizine hcl c18h23cln2 cid 6420019 structure, chemical names, physical and chemical properties, classification, patents, literature, biological. Cyclizine hydrochloride hazard statements h301 toxic if swallowed. Cyclizine is an antihistamine with sedative effect used to treat motion sickness. Sigmaaldrich offers a number of cyclizine hydrochloride products. Product name cyclizine hydrochloride cas number 303253 ec number 20669 chemical formula chcln. Its iupac name is called 1benzhydryl4methylpiperazine hydrochloride.
Dec 19, 2018 what other drugs will affect cyclizine bonine for kids, cyclivert, marezine. Parenteral cyclizine is indicated for the treatment of nausea and vomiting of motion sickness when the oral route cannot be used. Cyclizine, sold under a number of brand names, is a medication used to treat and prevent nausea, vomiting and dizziness due to motion sickness or vertigo. Cyclizine hydrochloride summary of product characteristics free download as powerpoint presentation.
Cyclizine side effects, dosage, interactions drugs. Suicide due to cyclizine overdose journal of analytical. Disclaimer the sds samples above are collected from the internet by chemblink and displayed here for the tutorial purpose only. Cyclizine hydrochloride tablets contain the active ingredient cyclizine hydrochloride, which belongs to a group of medicines called antihistamines which can be used to help stop you feeling sick nausea or being sick vomiting. Cyclizine tablets may have additive effects with alcohol and other central nervous system depressants e. Cool the filtrate in an ice bath, add a slight excess of 1 n sodium hydroxide, and stir well. Taking this medicine with other drugs that make you sleepy or slow your breathing can worsen these effects. Compare cyclizine vs cyclizine hcl comprehensive analysis.